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OtherClinical Practice Guidelines
Open Access

The Saudi clinical practice guideline for the prophylaxis of venous thromboembolism in medical and critically ill patients

Fahad M. Al-Hameed, Hasan M. Al-Dorzi, Mohamed A. Abdelaal, Ali Alaklabi, Ebtisam Bakhsh, Yousef A. Alomi, Mohammad Al Baik, Salah Aldahan, Holger Schünemann, Jan Brozek, Wojtek Wiercioch, Andrea J. Darzi, Reem Waziry and Elie A. Akl
Saudi Medical Journal November 2016, 37 (11) 1279-1293; DOI: https://doi.org/10.15537/smj.2016.11.15268
Fahad M. Al-Hameed
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Hasan M. Al-Dorzi
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Mohamed A. Abdelaal
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Ali Alaklabi
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Ebtisam Bakhsh
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Yousef A. Alomi
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Mohammad Al Baik
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Salah Aldahan
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Holger Schünemann
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
MD, PhD
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Jan Brozek
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Wojtek Wiercioch
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Andrea J. Darzi
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Reem Waziry
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Elie A. Akl
From the Intensive Care Department (Al-Hameed), Hematology Department (Abdelaal), College of Medicine, the Department of Medicine (Alaklabi), King Saud bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, National Guard Health Affairs, Jeddah, the Intensive Care Department (Al-Dorzi), King Abdulaziz Medical City, National Guard Health Affairs, the Department of Clinical Sciences (Bakhsh), College of Medicine, Princess Nourah Bint Abdulrahman University, the General Administration of Pharmaceutical Care (Alomi), Ministry of Health, the Department of Family and Community Medicine (Al Baik, Aldahan), Prince Sultan Medical Military City, Riyadh, Kingdom of Saudi Arabia, the Department of Medicine (Schünemann, Brozek), the Department of Clinical Epidemiology and Biostatistics (Schünemann, Brozek, Akl), McMaster University, Hamilton, Canada, Faculty of Health Sciences (Schünemann, Brozek, Akl, Wiercioch), American University of Beirut, the Department of Internal Medicine (Akl), American University of Beirut, Beirut, Lebanon, and the Faculty of Medicine (Darzi, Waziry), The Kirby Institute University of New South Wales, New South Wales, Australia
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Abstract

Venous thromboembolism (VTE) acquired during hospitalization is common, yet preventable by the proper implementation of thromboprophylaxis which remains to be underutilized worldwide. As a result of an initiative by the Saudi Ministry of Health to improve medical practices in the country, an expert panel led by the Saudi Association for Venous Thrombo Embolism (SAVTE; a subsidiary of the Saudi Thoracic Society) with the methodological guidance of the McMaster University Guideline working group, produced this clinical practice guideline to assist healthcare providers in VTE prevention. The expert part panel issued ten recommendations addressing 10 prioritized questions in the following areas: thromboprophylaxis in acutely ill medical patients (Recommendations 1-5), thromboprophylaxis in critically ill medical patients (Recommendations 6-9), and thromboprophylaxis in chronically ill patients (Recommendation 10). The corresponding recommendations were generated following the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach.

  • Received May 8, 2016.
  • Accepted August 24, 2016.
  • Copyright: © Saudi Medical Journal

This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Saudi Medical Journal: 37 (11)
Saudi Medical Journal
Vol. 37, Issue 11
1 Nov 2016
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The Saudi clinical practice guideline for the prophylaxis of venous thromboembolism in medical and critically ill patients
Fahad M. Al-Hameed, Hasan M. Al-Dorzi, Mohamed A. Abdelaal, Ali Alaklabi, Ebtisam Bakhsh, Yousef A. Alomi, Mohammad Al Baik, Salah Aldahan, Holger Schünemann, Jan Brozek, Wojtek Wiercioch, Andrea J. Darzi, Reem Waziry, Elie A. Akl
Saudi Medical Journal Nov 2016, 37 (11) 1279-1293; DOI: 10.15537/smj.2016.11.15268

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The Saudi clinical practice guideline for the prophylaxis of venous thromboembolism in medical and critically ill patients
Fahad M. Al-Hameed, Hasan M. Al-Dorzi, Mohamed A. Abdelaal, Ali Alaklabi, Ebtisam Bakhsh, Yousef A. Alomi, Mohammad Al Baik, Salah Aldahan, Holger Schünemann, Jan Brozek, Wojtek Wiercioch, Andrea J. Darzi, Reem Waziry, Elie A. Akl
Saudi Medical Journal Nov 2016, 37 (11) 1279-1293; DOI: 10.15537/smj.2016.11.15268
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© 2025 Saudi Medical Journal Saudi Medical Journal is copyright under the Berne Convention and the International Copyright Convention.  Saudi Medical Journal is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. Electronic ISSN 1658-3175. Print ISSN 0379-5284.

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