RT Journal Article
SR Electronic
T1 Pseudocholinesterase levels in patients under electroconvulsive therapy
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 103
OP 106
DO 10.15537/smj.2018.1.21307
VO 39
IS 1
A1 Küçükosman, Gamze
A1 Pişkin, Özcan
A1 Hancı, Volkan
A1 Okyay, Rahşan D.
A1 Ayoğlu, Hilal
A1 Yurtlu, Bülent S.
A1 Akın, Mehmet
A1 Turan, Işıl
YR 2018
UL http://smj.org.sa/content/39/1/103.abstract
AB Objectives: In this study, we aimed to retrospectively assess the correlation of pseudocholinesterase (PChE) levels with age, gender, body weight and diagnosed psychiatric diseases in electroconvulsive therapy (ECT) cases.Methods: This retrospective study was conducted at Bülent Ecevit University Hospital, Zonguldak, Turkey, between 2007 and 2011. In the study, 193 ECT case files were retrospectively scanned to evaluate PChE values before ECT and other file information.Results: There was no difference between gender in terms of PChE levels. Correlation analysis determined a weakly positive correlation between age (p=0.013; correlation coefficient [cc]: 0.178) and body weight (p<0.001; cc: 0.273) and PChE levels. No correlation was found between age, gender, weight or psychiatric diagnosis, and PChE levels.Conclusion: Neuromuscular blockage is a significant factor that increases patient safety, while increasing the efficacy of ECT. In choosing muscle relaxant agents, both patient factors and the pharmacological properties of the neuromuscular blocker should be considered. We think that in situations with delayed recovery of ECT cases without identified PChE levels, low PChE levels must be considered.