- Antibacterial activity of thymoquinone against pathogenic bacterial strains.
| Organism | Origin | Thymoquinone | ||
|---|---|---|---|---|
| Zone of inhibition (50 μg/ml) | μg/ml | |||
| mm Mean (SD) | MIC Mean (SD) | MBC Mean (SD) | ||
| Gram negative bacteria | ||||
| Pseudomonas aeruginosa (ATCC 27853) | ATCC | - | - | - |
| Escherichia coli (ATCC 25922) | ATCC | - | - | - |
| Pseudomonas | Clinical | - | - | - |
| Salmonella typhi | Clinical | - | - | - |
| Klebsiella pneumoniae | Clinical | 15 (2) | 1.30 (0.45) | 33.33 (14.43) |
| Shigella | Clinical | - | - | - |
| Escherichia coli | Clinical | - | - | - |
| Gram positive bacteria | ||||
| Enterococcus faecalis (ATCC 29212) | ATCC | - | - | - |
| Staphylococcus epidermidis (ATCC 12228) | ATCC | 17 (1.73) | 1.04 (0.45) | 10.41 (3.60) |
| Mycobacterium smegmatis | Clinical | - | - | - |
| Staphylococcus aureus | Clinical | 15 (1) | 2.60 (0.90) | 41 (14.43) |
| Staphylococcus saprophyticus | Clinical | - | - | - |
| Staphylococcus epidermidis | Clinical | 13 (1.73) | 8.3 (3.60) | 66.66 (28.86) |
| Streptococcus pyogenes | Clinical | - | - | - |
-: no effect, MIC: minimum inhibitory concentration, MBC: minimum bactericidal concentration, ATCC: American Type Culture Collection