Purpose : Long-term prostate cancer specific mortality after radical prostatectomy is poorly
defined in the era of widespread screening. An understanding of the treated natural history of …

Background The natural history of prostate-specific antigen (PSA)-defined biochemical
recurrence (BCR) of prostate cancer (PCa) after definitive local therapy is highly variable. …

Background Innovations in imaging and molecular characterisation and the evolution of new
therapies have improved outcomes in advanced prostate cancer. Nonetheless, we continue …

Purpose : Radical prostatectomy, external beam radiotherapy and brachytherapy are accepted
treatments for localized prostate cancer. However, it is unknown if survival differences …

Background Innovations in imaging and molecular characterisation together with novel
treatment options have improved outcomes in advanced prostate cancer. However, we still lack …

Background Innovations in treatments, imaging, and molecular characterisation in advanced
prostate cancer have improved outcomes, but various areas of management still lack high-…

Background Continuous diabetes-associated complications are a major source of immune
system exhaustion and an increased incidence of infection. Diabetes can cause poor …

Background Positive surgical margins (PSMs) in radical prostatectomy (RP) specimens are
a frequent indication for adjuvant radiotherapy and are used as a measure of surgical quality. …

Cancer is a universal public health problem. It is a leading cause of death worldwide, accounting
for an estimated 9.6 million deaths in 2018. More than half of all cancers (56.8%) and …

Multiple myeloma (MM) is a clonal disease of plasma cells that reside in the bone marrow (BM).
MM is an incurable disease; thus, screening for novel anti-myeloma drugs remains …