User profiles for Ali S. Jawad

Ali SM Jawad

Professor of Rheumatology, QMUL
Verified email at nhs.net
Cited by 2816

The effect of ethnicity and genetic ancestry on the epidemiology, clinical features and outcome of systemic lupus erythematosus

MJ Lewis, AS Jawad - Rheumatology, 2017 - academic.oup.com
In this in-depth review, we examine the worldwide epidemiology of SLE and summarize
current knowledge on the influence of race/ethnicity on clinical manifestations, disease activity, …

TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases

J Bystrom, FI Clanchy, TE Taher, P Mangat, AS Jawad… - Cytokine, 2018 - Elsevier
TNFα is a principal pro-inflammatory cytokine vital for immunity to infections. However, its
excessive production is involved in chronic inflammation and disease pathology in …

[HTML][HTML] Th17 lymphocytes in respiratory syncytial virus infection

J Bystrom, N Al-Adhoubi, M Al-Bogami, AS Jawad… - Viruses, 2013 - mdpi.com
Infection by respiratory syncytial virus (RSV) affects approximately 33 million infants annually
worldwide and is a major cause of hospitalizations. Helper T lymphocytes (Th) play a …

Heterogeneous yet stable Vδ2(+) T-cell profiles define distinct cytotoxic effector potentials in healthy human individuals

…, N Izotova, CL Grandjean, AS Jawad… - Proceedings of the …, 2016 - National Acad Sciences
Human γδ T cells display potent responses to pathogens and malignancies. Of particular
interest are those expressing a γδ T-cell receptor (TCR) incorporating TCRδ-chain variable-…

[HTML][HTML] Harnessing the therapeutic potential of Th17 cells

…, FI Clanchy, P Mangat, AS Jawad… - Mediators of …, 2015 - hindawi.com
Th17 cells provide protective immunity to infections by fungi and extracellular bacteria as
well as cancer but are also involved in chronic inflammation. The cells were first identified by …

[HTML][HTML] Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

…, A Ali, A Ali, FR Ali, J Ali, M Ali, M Ali, O Ali, S Ali, S Ali… - The Lancet, 2021 - thelancet.com
Background Azithromycin has been proposed as a treatment for COVID-19 on the basis of its
immunomodulatory actions. We aimed to evaluate the safety and efficacy of azithromycin in …

Clinical review: familial mediterranean fever—an overview of pathogenesis, symptoms, ocular manifestations, and treatment

…, M Stanford, F Fortune, AS Jawad - Ocular Immunology and …, 2016 - Taylor & Francis
Familial Mediterranean fever is an autoinflammatory multisystem disease, which most
commonly affects patients from the Mediterranean basin. This review discusses the common …

[HTML][HTML] Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF+ T Lymphocytes

…, S Alzabin, P Mangat, AS Jawad… - Clinical reviews in …, 2017 - Springer
Biologic TNFα inhibitors are a mainstay treatment option for patients with rheumatoid arthritis
(RA) refractory to other treatment options. However, many patients either do not respond or …

A survey on electric vehicle transportation within smart grid system

…, J Khan, U Farid, M Majid, SM Anwar, M Jawad… - … and Sustainable Energy …, 2018 - Elsevier
The electrification of hybrid electric vehicle reduces the reliance of transportation on fossil
fuels and reduces Green House Gas emissions. The economic and environmental benefits of …

A survey on consumers empowerment, communication technologies, and renewable generation penetration within Smart Grid

…, SM Ali, CA Mehmood, B Khan, M Jawad… - … and Sustainable Energy …, 2018 - Elsevier
The Smart Grid (SG) is a technological transformation from conventional electric grid, electro-mechanically
controlled system, to smart, intelligent, and electronically controlled system …