User profiles for Ayed A. Dera
Ayed A. DeraAssociate professor of Clinical Biochemistry Verified email at kku.edu.sa Cited by 805 |
[HTML][HTML] Recent developments in natural biopolymer based drug delivery systems
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
[HTML][HTML] Circulating microRNAs as potential diagnostic biomarkers for osteoporosis
Osteoporosis is the most common age-related bone disease worldwide and is usually clinically
asymptomatic until the first fracture happens. MicroRNAs are critical molecular regulators …
asymptomatic until the first fracture happens. MicroRNAs are critical molecular regulators …
Bone morphogenetic protein (BMP) 9 in cancer development: mechanistic, diagnostic, and therapeutic approaches?
…, Z Muhammed Mahdi, F Alsaikhan, AA Dera - Journal of Drug …, 2023 - Taylor & Francis
Bone morphogenetic protein (BMP)-9 is considered a member of the transforming growth
factor (TGF)β superfamily. It was first found as an inducer of bone and cartilage formation and …
factor (TGF)β superfamily. It was first found as an inducer of bone and cartilage formation and …
[HTML][HTML] Synthesis, molecular docking and ADMET studies of bis-benzimidazole-based thiadiazole derivatives as potent inhibitors, in vitro α-amylase and α …
Different research synthetic methods have been developed recently for the synthesis of bis-benzimidazole
analogs to investigate various biological significances. In this present study, …
analogs to investigate various biological significances. In this present study, …
[HTML][HTML] Designing multi-epitope monkeypox virus-specific vaccine using immunoinformatics approach
Background Monkeypox virus is an enveloped DNA virus that belongs to Poxviridae family.
The virus is transmitted from rodents to primates via infected body fluids, skin lesions, and …
The virus is transmitted from rodents to primates via infected body fluids, skin lesions, and …
Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling
M Al Fayi, H Otifi, M Alshyarba, AA Dera… - Journal of Drug …, 2020 - Taylor & Francis
This study evaluates the protective effects of Thymoquinone (Tq) and Curcumin (Cur) in models
of cisplatin-induced renal toxicity. Proliferation studies were carried out in HEK-293 cells. …
of cisplatin-induced renal toxicity. Proliferation studies were carried out in HEK-293 cells. …
[HTML][HTML] Synthesis of novel benzimidazole-based thiazole derivatives as multipotent inhibitors of α-amylase and α-glucosidase: in vitro evaluation along with molecular …
In this study, hybrid analogs of benzimidazole containing a thiazole moiety (1–17) were
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when compared …
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when compared …
[HTML][HTML] Comparative Insights into the Antimicrobial, Antioxidant, and Nutritional Potential of the Solanum nigrum Complex
Highlights (1) Against the seven bacteria tested, the five taxa studied had varying antibacterial
activity. (2) Plant extracts were discovered to be as efficient as antibiotics in certain …
activity. (2) Plant extracts were discovered to be as efficient as antibiotics in certain …
[HTML][HTML] Bioinformatics approach for the construction of multiple epitope vaccine against omicron variant of SARS-CoV-2
The World Health Organization categorized SARS-CoV-2 as a variant of concern, having
numerous mutations in spike protein, which have been found to evade the effect of antibodies …
numerous mutations in spike protein, which have been found to evade the effect of antibodies …
[HTML][HTML] New biologically hybrid pharmacophore thiazolidinone-based indole derivatives: synthesis, in vitro alpha-amylase and alpha-glucosidase along with …
Amylase and glucosidase enzymes are the primary harmful source in the development of
the chronic condition known as diabetes mellitus. The main function of these enzymes is to …
the chronic condition known as diabetes mellitus. The main function of these enzymes is to …