User profiles for Ayed A. Dera

Ayed A. Dera

Associate professor of Clinical Biochemistry
Verified email at kku.edu.sa
Cited by 805

[HTML][HTML] Recent developments in natural biopolymer based drug delivery systems

…, M Shah, S Iqbal, M Rehman, F Jaber, AA Dera… - RSC …, 2023 - pubs.rsc.org
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

[HTML][HTML] Circulating microRNAs as potential diagnostic biomarkers for osteoporosis

…, S Vinjamuri, RVT Hof, S Hamill, G Czanner, AA Dera… - Scientific reports, 2018 - nature.com
Osteoporosis is the most common age-related bone disease worldwide and is usually clinically
asymptomatic until the first fracture happens. MicroRNAs are critical molecular regulators …

Bone morphogenetic protein (BMP) 9 in cancer development: mechanistic, diagnostic, and therapeutic approaches?

…, Z Muhammed Mahdi, F Alsaikhan, AA Dera - Journal of Drug …, 2023 - Taylor & Francis
Bone morphogenetic protein (BMP)-9 is considered a member of the transforming growth
factor (TGF)β superfamily. It was first found as an inducer of bone and cartilage formation and …

[HTML][HTML] Synthesis, molecular docking and ADMET studies of bis-benzimidazole-based thiadiazole derivatives as potent inhibitors, in vitro α-amylase and α …

…, M Shah, F Ali, AM Fouda, Y Khan, AA Dera… - Arabian Journal of …, 2023 - Elsevier
Different research synthetic methods have been developed recently for the synthesis of bis-benzimidazole
analogs to investigate various biological significances. In this present study, …

[HTML][HTML] Designing multi-epitope monkeypox virus-specific vaccine using immunoinformatics approach

S Zaib, N Rana, N Hussain, H Alrbyawi, AA Dera… - Journal of Infection and …, 2023 - Elsevier
Background Monkeypox virus is an enveloped DNA virus that belongs to Poxviridae family.
The virus is transmitted from rodents to primates via infected body fluids, skin lesions, and …

Thymoquinone and curcumin combination protects cisplatin-induced kidney injury, nephrotoxicity by attenuating NFκB, KIM-1 and ameliorating Nrf2/HO-1 signalling

M Al Fayi, H Otifi, M Alshyarba, AA Dera… - Journal of Drug …, 2020 - Taylor & Francis
This study evaluates the protective effects of Thymoquinone (Tq) and Curcumin (Cur) in models
of cisplatin-induced renal toxicity. Proliferation studies were carried out in HEK-293 cells. …

[HTML][HTML] Synthesis of novel benzimidazole-based thiazole derivatives as multipotent inhibitors of α-amylase and α-glucosidase: in vitro evaluation along with molecular …

…, W Rehman, S Khan, L Rasheed, F Rahim, AA Dera… - Molecules, 2022 - mdpi.com
In this study, hybrid analogs of benzimidazole containing a thiazole moiety (1–17) were
afforded and then tested for their ability to inhibit α-amylase and α-glucosidase when compared …

[HTML][HTML] Comparative Insights into the Antimicrobial, Antioxidant, and Nutritional Potential of the Solanum nigrum Complex

…, TA Kurniawan, Z Khan, S Nadeem, M Javed, AA Dera… - Processes, 2022 - mdpi.com
Highlights (1) Against the seven bacteria tested, the five taxa studied had varying antibacterial
activity. (2) Plant extracts were discovered to be as efficient as antibiotics in certain …

[HTML][HTML] Bioinformatics approach for the construction of multiple epitope vaccine against omicron variant of SARS-CoV-2

…, F Akram, ST Liaqat, MZ Altaf, I Khan, AA Dera… - Scientific Reports, 2022 - nature.com
The World Health Organization categorized SARS-CoV-2 as a variant of concern, having
numerous mutations in spike protein, which have been found to evade the effect of antibodies …

[HTML][HTML] New biologically hybrid pharmacophore thiazolidinone-based indole derivatives: synthesis, in vitro alpha-amylase and alpha-glucosidase along with …

…, M Shah, R Hussain, H Alrbyawi, W Rehman, AA Dera… - Molecules, 2022 - mdpi.com
Amylase and glucosidase enzymes are the primary harmful source in the development of
the chronic condition known as diabetes mellitus. The main function of these enzymes is to …