Mutations in 11β-hydroxysteroid dehydrogenase type 2 gene (HSD11B2) cause an extraordinarily
rare autosomal recessive disorder, apparent mineralocorticoid excess (AME). AME is …

… Hanan Al Azkawi … Hanan Al Azkawi … It is not an uncommon phenomenon and is
prevalent in 40% to 65% of pubertal males. However, prepubertal gynecomastia …

Objectives: To report the genotype-phenotype characteristics, demographic features and
clinical outcome of Omani patients with congenital hyperinsulinism (CHI). Methods: We …

There are no adequate data that evaluate the safety and effectiveness of lowering triglyceride
levels in very young children. The authors report a family with two male siblings, 7 and 4 …

Background: Neonatal diabetes mellitus (NDM) is a rare disorder worldwide where diabetes
is diagnosed in the first 6 months of life. However, Oman has a relatively high incidence of …

Hypocalcemia is a rare but reversible cause of dilated cardiomyopathy with limited cases
being reported in the literature. Vitamin D deficiency is the main cause of hypocalcemia in …

Apparent mineralocorticoid excess (AME) is a rare autosomal recessive genetic disorder
causing severe … We conclude that this novel mutation is responsible for AME in this family. …

This is the first case report in Oman and the Gulf region of a 17-β-hydroxysteroid dehydrogenase
type 3 (17-β-HSD3) deficiency with a novel mutation in the HSD17B3 gene that has not …

The global disease pattern has shifted, with a more dominant prevalence of chronic disease
such as type 2 diabetes, metabolic syndrome, cancer and cardiovascular diseases. The inter…