Objectives: To investigate the period prevalence and risk factors for clinically important
prescription and monitoring errors among adults managed in community care in Saudi Arabia (SA…

The bottom-up production of chiral gold nanomaterials holds great potential for the advancement
of biosensing and nano-optics, among other applications. Reproducible preparations …

A robust and reproducible methodology to prepare stable inorganic nanoparticles with chiral
morphology may hold the key to the practical utilization of these materials. An optimized …

Besides functioning as the plasma transporter of retinol and thyroxine, TTR (transthyretin) is
a protease, cleaving apoA-I (apolipoprotein AI) after a phenylalanine residue. In the present …

Introduction Synovial hyperplasia is a main feature of rheumatoid arthritis pathology that
leads to cartilage and bone damage in the inflamed joints. Impaired apoptosis of resident …

… This project was supported by grant PI02/0713 form the Instituto de Salud Carlos III (Spain)
with participation of funds from FEDER (European Union), and by a grant of the Fundacion …

… We determined a k cat /K m value of 408.8 s −1 ·M −1 for the active fraction of TTR (7%),
which translates to an effective k cat /K m value of 6.0×10 3 s −1 ·M −1 . In comparison with other …

Chiral plasmonics is a rapidly developing field where breakthroughs and unsolved problems
coexist. We have recently reported binary surfactant-assisted seeded growth of chiral gold …

Transthyretin (TTR) has a well-established role in neuroprotection in Alzheimer's Disease (AD).
We have setup a drug discovery program of small-molecule compounds that act as …

This paper provides a number of epistemological and methodological reflections on modeling
and simulation through system dynamics and the special type of knowledge provided by …