Objectives: Persistent disease activity is associated with a poor prognosis in inflammatory
bowel disease (IBD). Therefore, monitoring of patients with intent to suppress subclinical …

Objective Although the Geboes score (GS) and modified Riley score (MRS) are commonly
used to evaluate histological disease activity in UC, their operating properties are unknown. …

Background Endoscopic assessment of mucosal disease activity is routinely used to
determine eligibility and response to therapy in clinical trials of ulcerative colitis. The operating …

Background Disease activity can be determined using clinical, endoscopic or histologic criteria
in patients with ulcerative colitis (UC). Persistent disease activity is associated with poor …

Background and Objectives: Colorectal cancer (CRC) is a major health problem in the
Kingdom of SaudiArabia (KSA). Our aim was to characterize the epidemiology of CRC in the …

Background Ulcerative colitis (UC) is an idiopathic inflammatory disorder. Currently, the
main goals of treatment are to induce and maintain clinical and/or endoscopic remission. …

Background Assessment of endoscopic disease activity, as measured by various endoscopic
evaluative instruments, is an essential part of quantifying disease activity in clinical trials in …

Results: Five hundred participants were included. The mean age was 41.0 years (SD 10.7).
Males were 50% and only 6.7% of those between 50 and 55 years of age had undergone …

Objective Histopathology is potentially an important outcome measure in UC. Multiple
histological disease activity (HA) indices, including the Geboes score (GS) and modified Riley …

Background We performed a systematic review to evaluate the efficacy and safety of
vedolizumab for induction and maintenance of remission in ulcerative colitis. Methods A literature …