[HTML][HTML] Protective effects of pomegranate (Punica granatum) juice on testes against carbon tetrachloride intoxication in rats

EM Al-Olayan, MF El-Khadragy, DM Metwally… - … and alternative medicine, 2014 - Springer
Background Pomegranate fruit has been extensively used as a natural medicine in many
cultures. The present study was aimed at evaluating the protective effects of pomegranate (…

[HTML][HTML] The Potential Protective Effect of Physalis peruviana L. against Carbon Tetrachloride-Induced Hepatotoxicity in Rats Is Mediated by Suppression of Oxidative …

EM Al-Olayan, MF El-Khadragy, AM Aref… - … medicine and cellular …, 2014 - hindawi.com
The active constituent profile in Cape gooseberry (Physalis peruviana L.) juice was determined
by GC-MS. Quercetin and kaempferol were active components in the juice. In this study …

[HTML][HTML] Antagonistic efficacy of luteolin against lead acetate exposure-associated with hepatotoxicity is mediated via antioxidant, anti-inflammatory, and anti-apoptotic …

…, RB Kassab, AE Abdel Moneim, MF El-Khadragy - Antioxidants, 2019 - mdpi.com
The abundant use of lead (Pb; toxic heavy metal) worldwide has increased occupational
and ecosystem exposure, with subsequent negative health effects. The flavonoid luteolin (LUT) …

[HTML][HTML] The neuroprotective role of coenzyme Q10 against lead acetate-induced neurotoxicity is mediated by antioxidant, anti-inflammatory and anti-apoptotic …

…, DM Metwally, MF El-Khadragy… - International journal of …, 2019 - mdpi.com
Heavy metal exposure, in lead (Pb) particularly, is associated with severe neuronal impairment
though oxidative stress mediated by reactive oxygen species, and antioxidants may be …

[HTML][HTML] Coenzyme Q10 activates the antioxidant machinery and inhibits the inflammatory and apoptotic cascades against lead acetate-induced renal injury in rats

…, DM Metwally, AEA Moneim, MF El-Khadragy - Frontiers in …, 2020 - frontiersin.org
The kidney is among the metabolic organs most susceptible to injury, particularly following
exposure to xenobiotics and heavy metals. We aimed to explore the potential protective …

[HTML][HTML] Effect of ginseng extract on the TGF-β1 signaling pathway in CCl4-induced liver fibrosis in rats

MM Hafez, SS Hamed, MF El-Khadragy… - … and alternative medicine, 2017 - Springer
Background Liver diseases are major global health problems. Ginseng extract has antioxidant,
immune-modulatory and anti-inflammatory activities. This study investigated the effect of …

[HTML][HTML] Green Coffea arabica Extract Ameliorates Testicular Injury in High-Fat Diet/Streptozotocin-Induced Diabetes in Rats

WA Al-Megrin, MF El-Khadragy, MH Hussein… - Journal of Diabetes …, 2020 - hindawi.com
Diabetes mellitus (DM) is a chronic endocrine disease characterized by persistent hyperglycemia.
Oxidative damage, inflammatory cytokines, and apoptotic cell death play a major role …

[HTML][HTML] Prevalence and morphological investigation of parasitic infection in freshwater fish (Nile tilapia) from Upper Egypt

…, HI Mohamed, BM Alrashdi, AK Dyab, MF El-Khadragy… - Animals, 2023 - mdpi.com
Simple Summary Fresh water Nile tilapia can be infected by numerous parasites, which can
result in high mortality and significant economic losses. The early detection of parasites and …

Chlorogenic acid abates male reproductive dysfunction in arsenic-exposed mice via attenuation of testicular oxido-inflammatory stress and apoptotic responses

MF El-Khadragy, WA Al-Megrin, S Alomar… - Chemico-biological …, 2021 - Elsevier
Arsenic, a major environmental pollutant of global concern, is well-known for its reproductive
toxicity. In this study, the protective potential of chlorogenic acid (CGA), a caffeoylquinic …

[HTML][HTML] Chlorogenic acid confers robust neuroprotection against arsenite toxicity in mice by reversing oxidative stress, inflammation, and apoptosis

DM Metwally, RA Alajmi, MF El-Khadragy… - Journal of functional …, 2020 - Elsevier
Arsenic is a potent neurotoxic xenobiotic found in drinking water, and food. Chlorogenic
acid (CGA), an abundant polyphenol in coffee, potentially has a wide range of therapeutic …