The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities

…, M Haris, SK Batra, B Alshehri, RS Al-Baradie… - Cellular Oncology, 2021 - Springer
Background Breast cancer (BC), the second most common cause of cancer-related deaths,
remains a significant threat to the health and wellness of women worldwide. The tumor …

[HTML][HTML] DNA methylation in stroke. Update of latest advances

…, C Carrera, E Muiño, N Torres, R Al-Baradie… - Computational and …, 2018 - Elsevier
Epigenetic modifications are hereditable and modifiable factors that do not alter the DNA
sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-…

[HTML][HTML] Citicoline induces angiogenesis improving survival of vascular/human brain microvessel endothelial cells through pathways involving ERK1/2 and insulin …

…, M Abudawood, S Matou-Nasri, R Al-Baradie… - Vascular Cell, 2012 - Springer
Background Citicoline is one of the neuroprotective agents that have been used as a therapy
in stroke patients. There is limited published data describing the mechanisms through …

[HTML][HTML] Monomeric C-reactive protein localized in the cerebral tissue of damaged vascular brain regions is associated with neuro-inflammation and …

RS Al-Baradie, S Pu, D Liu, Y Zeinolabediny… - Frontiers in …, 2021 - frontiersin.org
Monomeric C-reactive protein (mCRP) is now accepted as having a key role in modulating
inflammation and in particular, has been strongly associated with atherosclerotic arterial …

[HTML][HTML] Effect of transcranial direct current stimulation augmented with motor imagery and upper-limb functional training for upper-limb stroke rehabilitation: a …

FZ Kashoo, RS Al-Baradie, M Alzahrani… - International Journal of …, 2022 - mdpi.com
Background: Combining transcranial direct current stimulation (tDCS) with other therapies is
reported to produce promising results in patients with stroke. The purpose of the study was …

Transcriptomics-based characterization of the toxicity of ZnO nanoparticles against chronic myeloid leukemia cells

…, S Mickymaray, W Alturaiki, RS Al-Baradie… - International Journal …, 2020 - Taylor & Francis
Introduction Zinc oxide nanoparticles (ZnO NPs) have recently attracted attention as potential
anti-cancer agents. To the best of our knowledge, the toxicity of ZnO NPs against human …

Portable smart non-invasive hemoglobin measurement system

RS Al-Baradie, ASC Bose - 10th International Multi …, 2013 - ieeexplore.ieee.org
Analysis of blood substances such as hemoglobin, glucose, protein, cholesterol, etc. are
important parameters for health condition monitoring. Traditionally, blood sample is taken using …

Nanobodies as versatile tools: A focus on targeted tumor therapy, tumor imaging and diagnostics

RS Al-Baradie - Human Antibodies, 2020 - content.iospress.com
Monoclonal antibodies and vaccines have widely been studied for the immunotherapy of
cancer, though their large size appears to limit their functionality in solid tumors, in large part …

[HTML][HTML] Neuroprotective effect of endophytic fungal antioxidant polyphenols on cerebral ischemic stroke-induced Albino rats; memory impairments, brain damage, and …

…, ALB Raid, A Abdelhadi, A Al Othaim… - Journal of King Saud …, 2023 - Elsevier
Background Stroke is one of the leading causes of mortality and disability throughout the world.
Recently, antioxidant therapies were attempted to reduce apoptotic cell death in cerebral …

[PDF][PDF] Pathophysiology of strokes

MA Mir, RS Al-Baradie… - Recent Advances in Stroke …, 2014 - academia.edu
Once considered exclusively a disorder of blood vessels, growing evidence has led to the
realization that the biological processes underlying stroke are driven by the interaction of …