Melatonin, the neurohormone of the pineal gland, is also produced by various other tissues
and cells. It acts via G protein-coupled receptors expressed in various areas of the central …

Melatonin, an endogenous signal of darkness, is an important component of the body's
internal time-keeping system. As such it regulates major physiological processes including the …

This systematic review and meta-analysis evaluated the extent of sleep disturbances during
the COVID-19 pandemic. Eleven databases and six preprint repositories were searched for …

Good sleep is necessary for good physical and mental health and a good quality of life.
Insufficient sleep is a pervasive and prominent problem in the modern 24-h society. A …

Melatonin, originally discovered as a hormone of the pineal gland, is produced by bacteria,
protozoa, plants, fungi, invertebrates, and various extrapineal sites of vertebrates, including …

The circadian rhythm of melatonin in saliva or plasma, or of the melatonin metabolite 6-sulphatoxymelatonin
(aMT6S) in urine, is a defining feature of suprachiasmatic nucleus (SCN) …

Free vaccination against COVID-19 commenced in India on January 16, 2021, and the
government is urging all of its citizens to be immunized, in what is expected to be the largest …

The cyclic nature of depressive illness, the diurnal variations in its symptomatology and the
existence of disturbed sleep–wake and core body temperature rhythms, all suggest that …

The pineal product melatonin has remarkable antioxidant properties. It is secreted during
darkness and plays a key role in various physiological responses including regulation of …

The pineal product melatonin has remarkable antioxidant properties. It scavenges hydroxyl,
carbonate and various organic radicals, peroxynitrite and other reactive nitrogen species. …