Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to
infection (1). Sepsis and septic shock are major healthcare problems, impacting millions of …

Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Background The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of a rapidly spreading illness, Coronavirus Disease 2019 (COVID-19), affecting …

Objective: To update and expand the 2013 Clinical Practice Guidelines for the Management
of Pain, Agitation, and Delirium in Adult Patients in the ICU. Design:

Following the new ESPEN Standard Operating Procedures, the previous guidelines to
provide best medical nutritional therapy to critically ill patients have been updated. These …

Objectives To develop evidence-based recommendations for clinicians caring for children (including
infants, school-aged children, and adolescents) with septic shock and other sepsis-…

The main management strategies for treating cancer patients during the COVID‐19
epidemic include clear communication and education about hand hygiene, infection control …

Background Respiratory protective devices are critical in protecting against infection in
healthcare workers at high risk of novel 2019 coronavirus disease (COVID‐19); however, …

Purpose To provide evidence-based guidelines for early enteral nutrition (EEN) during
critical illness. Methods We aimed to compare EEN vs. early parenteral nutrition (PN) and vs. …

Background Supplemental oxygen is often administered liberally to acutely ill adults, but the
credibility of the evidence for this practice is unclear. We systematically reviewed the …