An unusual cause of elevated serum total βhCG
CL Buckner, L Wilson… - Annals of Clinical & …, 2007 - Assoc Clin Scientists
Human chorionic gonadotropin (hCG), a heterodimeric hormone consisting of an alpha (α)
and a beta (β) subunit, is used as a marker for the diagnosis of pregnancy, congenital …
and a beta (β) subunit, is used as a marker for the diagnosis of pregnancy, congenital …
Are laboratories reporting serum quantitative hCG results correctly?
Z Cao, R Rej - Clinical chemistry, 2008 - academic.oup.com
Background: Human chorionic gonadotropin (hCG) is a heterodimeric glycoprotein hormone
that exists in multiple forms. Immunoassays commonly used in clinical laboratories measure …
that exists in multiple forms. Immunoassays commonly used in clinical laboratories measure …
False-positive hCG assay results leading to unnecessary surgery and chemotherapy and needless occurrences of diabetes and coma
LA Cole, KM Rinne, S Shahabi, A Omrani - Clinical chemistry, 1999 - academic.oup.com
Much concern has been raised by the unraveling at the hCG Reference Service of six cases
of persistent phantom human chorionic gonadotropin (hCG). These are false-positive hCG …
of persistent phantom human chorionic gonadotropin (hCG). These are false-positive hCG …
Falsely decreased human chorionic gonadotropin (hCG) results due to increased concentrations of the free β subunit and the β core fragment in quantitative hCG …
BACKGROUND Earlier studies have shown that increased concentrations of certain human
chorionic gonadotropin (hCG) variants can cause false-negative results in some qualitative …
chorionic gonadotropin (hCG) variants can cause false-negative results in some qualitative …
Utility of commonly used commercial human chorionic gonadotropin immunoassays in the diagnosis and management of trophoblastic diseases
LA Cole, S Shahabi, SA Butler, H Mitchell… - Clinical …, 2001 - academic.oup.com
Background: Patients with trophoblastic diseases produce ordinary and irregular forms of
human chorionic gonadotropin (hCG; eg, nicked hCG, hCG missing the β-subunit C-terminal …
human chorionic gonadotropin (hCG; eg, nicked hCG, hCG missing the β-subunit C-terminal …
Method evaluation for total β-human chorionic gonadotropin using urine and the ADVIA centaur
AM Halldorsdottir, MO Carayannopoulos… - Clinical …, 2003 - academic.oup.com
We recently described the use of a quantitative serum human chorionic gonadotropin (hCG)
assay with urine samples (1). Quantitative urine hCG assays are important in validations of …
assay with urine samples (1). Quantitative urine hCG assays are important in validations of …
Human chorionic gonadotropin and associated molecules
LA Cole - Expert review of molecular diagnostics, 2009 - Taylor & Francis
When considering human chorionic gonadotropin (hCG) and hCG tests, it is important to
realize that it is not a single biological molecule. The regular form of hCG produced by …
realize that it is not a single biological molecule. The regular form of hCG produced by …
Determination of human chorionic gonadotropin
UH Stenman, H Alfthan - Best Practice & Research Clinical Endocrinology & …, 2013 - Elsevier
Determination of human chorionic gonadotropin (hCG) is used for diagnosis and monitoring
of pregnancy, pregnancy related disorders, for trophoblastic and some nontrophoblastic …
of pregnancy, pregnancy related disorders, for trophoblastic and some nontrophoblastic …
Discordant results in human chorionic gonadotropin assays
LA Cole, A Kardana - Clinical Chemistry, 1992 - academic.oup.com
Discordance has been reported in human chorionic gonadotropin (hCG) concentrations
measured by different immunoassay kits. We examined the results for 40 serum samples …
measured by different immunoassay kits. We examined the results for 40 serum samples …
Heterophile antibody blocking agent to confirm false positive serum human chorionic gonadotropin assay
N Esfandiari, JM Goldberg - Obstetrics & Gynecology, 2003 - journals.lww.com
BACKGROUND Persistently false positive human chorionic gonadotropin (hCG) test results
in the absence of an intrauterine pregnancy may lead to a diagnosis of ectopic pregnancy or …
in the absence of an intrauterine pregnancy may lead to a diagnosis of ectopic pregnancy or …