RT Journal Article SR Electronic T1 Towards safer surgery in patients with sickle cell disease JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1788 OP 1790 VO 28 IS 12 A1 AbdulWahed N. Meshikhes YR 2007 UL http://smj.org.sa/content/28/12/1788.abstract AB Surgery in patients with sickle cell disease (SCD) has been associated with high morbidity and mortality. In recent years, a marked improvement in the safety of surgery and anesthesia in this high-risk group of patients has been witnessed; owing to the improvements in surgical and anesthetic care, greater awareness of pathophysiology of the disease, proper perioperative preparation, and attention to factors predisposing to vasoocclusive crises. However, this is not paralleled by similar improvement in countries where the disease is not prevalent. Greater population mobility in recent years makes recognition of surgical manifestations of the disease, and awareness of perioperative management of sickle cell patients undergoing surgical interventions of paramount importance. This article aims to summarize steps towards safer surgery in patients with SCD.