RT Journal Article
SR Electronic
T1 Nalidixic acid-resistant Salmonella enterica serotype typhi infection presenting with sub-intestinal obstruction and mesenteric adenitis
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 129
OP 132
VO 29
IS 1
A1 Al-Khuwaitir, Tarig S.
A1 Al-Zuhair, Amin A.
A1 Al-Ghamdi, Ali G.
A1 Khan, Abdulaziz
YR 2008
UL http://smj.org.sa/content/29/1/129.abstract
AB Nalidixic acid-resistant Salmonella typhi NARST infections increase minimal inhibitory concentrations of fluoroquinolones, due to chromosomal mutations in the gene encoding DNA gyrase, and can lead to a delayed treatment response. This in turn alters the course of the disease allowing for a protracted period of illness and the occurrence of complications. In this case report, we present a patient from the Indian sub-continent, who was diagnosed with NARST complicated by sub-intestinal obstruction, her diagnosis, treatment, and subsequent recovery.