RT Journal Article
SR Electronic
T1 Effectiveness of a 20% Miswak extract against a mixture of Candida albicans and Enterococcus faecalis
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 640
OP 643
VO 31
IS 6
A1 Al-Obaida, Mohammad I.
A1 Al-Essa, Mohamed A.
A1 Asiri, Abdulaziz A.
A1 Al-Rahla, Ali A.
YR 2010
UL http://smj.org.sa/content/31/6/640.abstract
AB OBJECTIVE: To examine the in vitro antimicrobial effect of a 20% Miswak extract against a mixture of Candida albicans (C. albicans) and Enterococcus faecalis (E. faecalis) using the dilution tube susceptibility test, which allows direct contact between the tested material and the microorganisms.METHODS: The study samples were collected and processed between August 2009 and January 2010 in the College of Dentistry, King Saud University, Riyadh, Saudi Arabia. Each microorganism was obtained in a suspension and exposed to a 20% Miswak extract in plastic tissue culture clusters containing 24 wells. Six wells were used per group. The Miswak extract was incubated with the microorganisms for one, 6, and 24 hours.RESULTS: This in vitro study showed that Miswak extract was an effective antifungal and antibacterial agent at all tested experimental time periods, except one hour exposure of a 20% Miswak extract to E. faecalis and a mixture of E. faecalis and C. albicans, which was ineffective in inhibiting their growth.CONCLUSION: Twenty percent Miswak extract is an effective antifungal and antibacterial agent against C. albicans and E. faecalis.