PT  - JOURNAL ARTICLE
AU  - Alotaibi, Wadha M.
TI  - Severe hepatic dysfunction after sevoflurane exposure.
DP  - 2008 Sep 01
TA  - Saudi Medical Journal
PG  - 1344--1346
VI  - 29
IP  - 9
4099  - http://smj.org.sa/content/29/9/1344.short
4100  - http://smj.org.sa/content/29/9/1344.full
SO  - Saudi Med J2008 Sep 01; 29
AB  - Sevoflurane is thought to have a potential for hepatotoxicity. A few cases of hepatotoxicity have been reported since it was introduced in 1990 into clinical practice in Japan. The underlying pathophysiology of hepatotoxicity is nonspecific. We report a case of severe hepatic dysfunction after uneventful sevoflurane anesthesia in a child with posterior fossa resection of medulloblastoma. The case of sevoflurane being incriminated is unclear due to various confounding factors that is worthy of discussion.