RT Journal Article
SR Electronic
T1 Severe hepatic dysfunction after sevoflurane exposure.
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1344
OP 1346
VO 29
IS 9
A1 Alotaibi, Wadha M.
YR 2008
UL http://smj.org.sa/content/29/9/1344.abstract
AB Sevoflurane is thought to have a potential for hepatotoxicity. A few cases of hepatotoxicity have been reported since it was introduced in 1990 into clinical practice in Japan. The underlying pathophysiology of hepatotoxicity is nonspecific. We report a case of severe hepatic dysfunction after uneventful sevoflurane anesthesia in a child with posterior fossa resection of medulloblastoma. The case of sevoflurane being incriminated is unclear due to various confounding factors that is worthy of discussion.