RT Journal Article
SR Electronic
T1 p63 expression in randomized odontogenic cysts.
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 463
OP 466
VO 32
IS 5
A1 Seyedmajidi, Maryam
A1 Shafaee, Shahryar
A1 Shafigh, Ensieh
A1 Bijani, Ali
A1 Hamidi, Hamid
YR 2011
UL http://smj.org.sa/content/32/5/463.abstract
AB OBJECTIVES: To find out the immunohistochemical assessment of p63 expression in odontogenic cysts based on the differences among their clinical behaviors.METHODS: This study was carried out on 34 archival paraffin-embedded specimens of odontogenic cysts. We obtained the specimens from the Pathology Department of Babol University of Medical Sciences, Babol, Iran from March 2003 to February 2008. The specimens comprised 12 dentigerous cysts, 9 radicular cysts, and 13 keratocystic odontogenic tumors (KCOTs). The immunohistochemical technique was performed using the Envision system for evaluation of p63 expression.RESULTS: The KCOT revealed the highest p63 expression and the differences between the 3 groups was statistically significant.CONCLUSIONS: P63 expression might be helpful when identifying cyst types with more aggressive and invasive phenotype.