RT Journal Article
SR Electronic
T1 Apoptosis and eosinophils. Regulation and clinical relevance
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 643
OP 656
VO 29
IS 5
A1 Alenzi،, Faris Q
YR 2008
UL http://smj.org.sa/content/29/5/643.abstract
AB Apoptosis, or program cell death, is a process of fundamental biological importance, and eosinophil apoptosis is believed to be the primary mechanism for removing eosinophils from the lung followed by their recognition and phagocytosis by macrophages or resident bronchial epithelial cells. There is, therefore, an increased interest in the fundamental role of the signals and intracellular signaling molecules that initiate and control apoptosis in human eosinophils though much remains to be established. This article reviews briefly the cross talks between apoptosis and eosinophils and summarizes the recent developments in this field.