RT Journal Article SR Electronic T1 A comparison of sevoflurane induction versus propofol induction for laryngeal mask airway insertion in elderly patients JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1124 OP 1129 VO 31 IS 10 A1 Derya Topuz A1 Aysun Postaci A1 Ozlem Sacan A1 Nurcan Yildiz A1 Bayazit Dikmen YR 2010 UL http://smj.org.sa/content/31/10/1124.abstract AB OBJECTIVE: To compare 8% or 5% sevoflurane and propofol induction according to the ease of laryngeal mask airway (LMA) placement and hemodynamic effects in elderly patients.METHODS: Ninety unpremedicated American Society of Anesthesiologists (ASA) I-III male patients >65 years, undergoing day case urological surgical intervention under general anesthesia at the Numune Education and Research Hospital, Ankara, Turkey between October 2008 to May 2009 were studied. The patients were group into 3 and were administered intravenous (intravenous) 5 ug/kg alfentanil before induction. Patients in group propofol (P) (n=29), anesthesia was induced 1.5 mg/kg propofol intravenous; in Group 8 (n=28) and Group 5 (n=28) anesthesia was induced with 8% and 5% sevoflurane in 60% nitrous oxide, and 40% oxygen with tidal-volume-breath (TVB).RESULTS: Induction times were as follows: in Group P = 54.76 ± 12.29 sec; Group 8 = 69.93 ± 18.76 sec, and in Group 5 = 92.14 ± 27.68 sec (p<0.01). Apnea duration was longer in Group P (6.55 ± 4.07 min.) than in group 8 (1.73 ± 2.49 min), and group 5 (1.12 ± 1.12 min) (p<0.01). The decrease in mean arterial pressure (MAP) before alfentanil (control) and after induction was significantly different between the groups.CONCLUSION: In elderly patients who will be administered day case anesthesia, in the placement of LMA, 5 ug/kg alfentanil followed by 5% sevoflurane induction by TVB method with minimal hemodynamic changes could be an alternative to propofol induction.