RT Journal Article SR Electronic T1 Preoperative use of analgesia in appendicitis JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 859 OP 862 VO 29 IS 6 A1 Aram, Fahmi O. YR 2008 UL http://smj.org.sa/content/29/6/859.abstract AB OBJECTIVE: To determine the influence of diclofenac sodium DS on masking the diagnosis of acute appendicitis.METHODS: A prospective, experimental study was carried out in Ibn Sinna General Hospital, Mukalla, Hadramout Governorate, Yemen from November 2006 to March 2007. The data were collected using a well designed questionnaire, with observation during the period of admission, prior to the operation.RESULTS: This study includes 80 patients 40 as cases, and 40 as controls, and the results revealed that most of the symptoms fever, anorexia, nausea, and vomiting, and signs tenderness, obturator and psoas signs, local guarding, and rigidity, were not hidden by DS p>0.05, while other symptoms pain, and signs rebound tenderness, Rovsing's, and pointing had been hindered by the use of DS. The most common presenting symptom in the placebo and DS group was pain 100%, which showed a marked decrease in severity in those who received DS as analgesia 72.2%.CONCLUSION: Some of the symptoms, and signs of acute appendicitis were masked by the use of analgesia, while others were not. In summary, DS did not influence the diagnosis or management of acute appendicitis.