PT  - JOURNAL ARTICLE
AU  - Shiva, Siamak
AU  - Behbahan, Afshin G.
TI  - Autoimmune thyroid disease in children and adolescents with type 1 diabetes mellitus in Northwest Iran
DP  - 2009 May 01
TA  - Saudi Medical Journal
PG  - 673--676
VI  - 30
IP  - 5
4099  - http://smj.org.sa/content/30/5/673.short
4100  - http://smj.org.sa/content/30/5/673.full
SO  - Saudi Med J2009 May 01; 30
AB  - OBJECTIVE: To investigate the prevalence of autoimmune thyroid disease in diabetic children in Northwest Iran.METHODS: In a cross-sectional study from February 2006 to November 2007, serum levels of anti-thyroid peroxidase, and anti-thyroglobulin antibodies, and thyrotropin hormone were measured with ELISA method in 176 diabetic children (78 Male and 98 Female) at a mean age of 8.3 ± 3.7 and mean diabetes duration of 1.6 ± 2.5 years, who were referred to the Pediatric-Endocrinology Clinic of Tabriz University of Medical Sciences, Tabriz, Iran.RESULTS: Autoimmune thyroid disease was found in 12% of patients (8.6% female, and 3.4% male). Significant levels were found for anti-thyroid peroxidase (10.2%), anti-thyroglobulin (8%), and both antibodies (6.3%) in all patients.CONCLUSION: We concluded that autoimmune thyroid disease in Iranian children, and adolescents with type 1 diabetes has a medium prevalence rate compared with those of other countries. The disease is more common in female, and older diabetic patients.