RT Journal Article
SR Electronic
T1 Autoimmune thyroid disease in children and adolescents with type 1 diabetes mellitus in Northwest Iran
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 673
OP 676
VO 30
IS 5
A1 Shiva, Siamak
A1 Behbahan, Afshin G.
YR 2009
UL http://smj.org.sa/content/30/5/673.abstract
AB OBJECTIVE: To investigate the prevalence of autoimmune thyroid disease in diabetic children in Northwest Iran.METHODS: In a cross-sectional study from February 2006 to November 2007, serum levels of anti-thyroid peroxidase, and anti-thyroglobulin antibodies, and thyrotropin hormone were measured with ELISA method in 176 diabetic children (78 Male and 98 Female) at a mean age of 8.3 ± 3.7 and mean diabetes duration of 1.6 ± 2.5 years, who were referred to the Pediatric-Endocrinology Clinic of Tabriz University of Medical Sciences, Tabriz, Iran.RESULTS: Autoimmune thyroid disease was found in 12% of patients (8.6% female, and 3.4% male). Significant levels were found for anti-thyroid peroxidase (10.2%), anti-thyroglobulin (8%), and both antibodies (6.3%) in all patients.CONCLUSION: We concluded that autoimmune thyroid disease in Iranian children, and adolescents with type 1 diabetes has a medium prevalence rate compared with those of other countries. The disease is more common in female, and older diabetic patients.