PT  - JOURNAL ARTICLE
AU  - Nasser, Tariq
AU  - Qari, Faiza
TI  - Pheochromocytoma, papillary thyroid carcinoma
DP  - 2009 Aug 01
TA  - Saudi Medical Journal
PG  - 1087--1090
VI  - 30
IP  - 8
4099  - http://smj.org.sa/content/30/8/1087.short
4100  - http://smj.org.sa/content/30/8/1087.full
SO  - Saudi Med J2009 Aug 01; 30
AB  - A 53-year-old woman presented with labile and difficult to control hypertension on 3 different anti-hypertensive medications. Abdominal computed tomography and ultrasonography of the thyroid gland showed a 1.8 cm thyroid nodule. Fine needle aspiration biopsy of the thyroid nodule revealed papillary thyroid carcinoma. Serum thyroid stimulating hormone and free thyroxine, calcitonin, carcinoembryonic antigen, intact parathyroid hormone, and calcium levels were within normal limits. A 24-hour urine metanephrine showed significant elevation in urine metanephrine of approximately 3 times the upper limit of normal, and the result of 131I-metaiodobenzyleguanjdjne (131I-MIBG) scintography confirmed that the adrenal mass was pheochromocytoma. Right adrenalectomy and total thyroidectomy were performed. The final pathology was pheochromocytoma and papillary thyroid carcinoma. An analysis of c-ret porto-oncogene mutation yielded a negative result. This unusual association of 2 tumors represents a new entity.