PT  - JOURNAL ARTICLE
AU  - Ali Cetinkaya
AU  - Kaniye Aydin
AU  - Hatice A. Sirakaya
AU  - Rumeysa Yilmaz
TI  - A loxoscelism case received therapeutic apheresis and hyperbaric oxygen therapy
AID  - 10.15537/smj.2020.12.25544
DP  - 2020 Dec 01
TA  - Saudi Medical Journal
PG  - 1364--1368
VI  - 41
IP  - 12
4099  - http://smj.org.sa/content/41/12/1364.short
4100  - http://smj.org.sa/content/41/12/1364.full
SO  - Saudi Med J2020 Dec 01; 41
AB  - Loxosceles reclusa (L.reclusa) is known to bite humans, and its venom includes several enzymes that cause clinical symptoms. Loxoscelism, a condition due to being bitten by Loxosceles spiders, commonly known as recluses, can involve a range of clinical conditions, from local cutaneous lesions to severe systemic involvement. The diagnosis of loxoscelism is usually made by anamnesis and clinical findings. Magnetic resonance imaging is recommended for patients at high risk of necrotizing fasciitis. Treatment modalities are still controversial and there is no standardized treatment approach. Reported here, our case of loxoscelism involved a 24-year-old man presenting with a Loxosceles spider bite, dermonecrotic lesion, vomiting, diarrhea, acute renal injury, and rhabdomyolysis, who was successfully treated with hyperbaric oxygen therapy, therapeutic apheresis, hemodialysis, wound debridement, and cutaneous autografting. Early diagnosis and multidisciplinary approach can be life-saving in spider bites that can cause systemic involvement. Loxoscelism should be considered in patients with skin necrosis, acute renal injury, and rhabdomyolysis.