PT  - JOURNAL ARTICLE
AU  - Abohamr, Samah I.
AU  - Abazid, Rami M.
AU  - Aldossari, Mubarak A.
AU  - Amer, Hala A.
AU  - Badhawi, Omar S.
AU  - Aljunaidi, Obaid M.
AU  - Alzarzour, Shaimaa H.
AU  - Saadeddin, Hiba M.
AU  - Bhat, Fayaz A.
AU  - Elsheikh, Eman
TI  - Clinical characteristics and in-hospital mortality of COVID-19 adult patients in Saudi Arabia
AID  - 10.15537/smj.2020.11.25495
DP  - 2020 Nov 01
TA  - Saudi Medical Journal
PG  - 1217--1226
VI  - 41
IP  - 11
4099  - http://smj.org.sa/content/41/11/1217.short
4100  - http://smj.org.sa/content/41/11/1217.full
SO  - Saudi Med J2020 Nov 01; 41
AB  - Objectives: To provide a detailed study of demographic, baseline comorbidities, clinical features, and outcome for Coronavirus disease 2019 (COVID-19) patients.Methods: A record-based case-series study conducted from March 23 to June 15, 2020 in King Saud Medical City, Riyadh, Saudi Arabia. Demographic data, clinical presentation, laboratory investigations, complications, and in-hospital outcome of COVID-19 patients collected with analysis of the clinical characteristics for survivors and deceased.Results: A total of 768 patients were included. The mean age was 46.36±13.7 years and 76.7% were men. Approximately 96.3% reported more than one comorbidity; diabetes mellitus was the most frequent (46.4%). Fever (84.5%), cough (82.3%), and shortness of breath (79.8%) were the main presenting symptoms. During the follow-up, pneumonia reported in 68.6%, acute respiratory distress syndrome in 32.7%, septic shock in 20.7%, respiratory failure in 20.3%, and acute kidney injury in 19.3%. Approximately 45.8% of enrolled patients required intensive care unit admission. Lung disease (odd ratio [OR]=3.862 with 95% confident interval [CI] (2.455-6.074), obesity (OR=3.732, CI=2.511-5.546), smoking (OR=2.991, CI=2.072-4.317), chronic kidney disease (OR=2.296. CI=1.497-3.521), and diabetes mellitus (OR=2.291, CI=1.714-3.063) are predictors of ICU admission. Fatality ratio was 89/2084 (4.27%). Men were more prevalent in dead group.Conclusion: Coronavirus disease 2019 places a huge burden on healthcare facilities, particularly in patients with comorbidity. Coronavirus disease 2019 patients who are obese and smokers with history of diabetes mellitus have a high risk of death.