TY - JOUR T1 - Acute cardiac injury is associated with adverse outcomes, including mortality in COVID-19 patients JF - Saudi Medical Journal JO - Saudi Med J SP - 1204 LP - 1210 DO - 10.15537/smj.2020.11.25466 VL - 41 IS - 11 AU - Kashif B. Naeem AU - Mahmood Y. Hachim AU - Ibrahim Y. Hachim AU - Ayman Chkhis AU - Rajesh Quadros AU - Haifa Hannawi AU - Issa Al Salmi AU - Fahdah Alokaily AU - Suad Hannawi Y1 - 2020/11/01 UR - http://smj.org.sa/content/41/11/1204.abstract N2 - Objectives: To evaluate acute cardiac injury in COVID-19 patients and its association with adverse outcomes including mortality in the United Arab Emirates (UAE) population.Methods: A retrospective study conducted between February and June 2020 in Dubai, UAE, for all laboratory-confirmed Coronavirus disease-19 patients. Demographic, clinical, laboratory, radiological, and clinical outcomes were compared between patients with and without acute cardiac injury.Results: During the study period, 203 patients were included, of which, 44 (21.7%) had evidence of acute cardiac injury. Compared with patients without acute cardiac injury, patients with acute cardiac injury were: older, had more shortness of breath, diabetes, hypertension, and more bilateral airspace shadowing on admission chest radiography. These patients also had a higher neutrophil count, C-reactive protein, procalcitonin, ferritin, D-dimers and lactate dehydrogenase but lower lymphocyte count. Regarding outcomes, these patients had higher intensive care admissions; a higher rate of complications including acute kidney and liver injury, acidosis, septic shock, acute respiratory distress syndrome, needed more mechanical ventilation, and had a significantly higher risk of death.Conclusion: Acute cardiac injury is common among Coronavirus disease-19 patients. These patients present with higher comorbidities, have high inflammatory markers and have greater risk for in-hospital multi-organ damage, need for mechanical ventilation, and death. Prompt full assessment and intervention are recommended. ER -