RT Journal Article SR Electronic T1 Outcomes of multidisciplinary team interventions in the management of sickle cell disease patients with opioid use disorders JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1104 OP 1110 DO 10.15537/smj.2020.10.25386 VO 41 IS 10 A1 Zahrani, Omar Al A1 Hanafy, Ehab A1 Mukhtar, Osama A1 Sanad, Ashraf A1 Yassin, Wael YR 2020 UL http://smj.org.sa/content/41/10/1104.abstract AB Objectives: To identify the magnitude of opioid use disorder (OUD) among sickle cell disease (SCD) patients; emphasize on multidisciplinary team (MDT) role; estimate cost-effectiveness following the proper use of therapeutic guidelines; and facilitate the reduction of emergency room (ER) visits and the length of stay (LOS).Methods: This retrospective cohort study included SCD patients aged 14 years and above, who have OUD. Data was collected between January 2016 and December 2018. Data included ER visits, hospital LOS, opioid consumption, and narcotic prescription tracking. The target group was followed with a set of interventions for pain management and healthcare resource utilization.Results: Twenty one SCD patients were identified with OUD. Following the interventions, there was a statistically significant decrease in ER visits of these OUD patients (from 8709 visits in 2016 to only 94 in 2018). Morphine consumption decreased by 82% and meperidine by 60%, over the 3-year period. Moreover, there was a huge reduction in both ER and LOS costs for this cohort of patients.Conclusion: Establishing an MDT and a series of interventions for SCD patients with OUD, including educational activities for caregivers and patients; establishing a palliative/pain clinic and a SCD addiction clinic; and implementing an adequate opioid prescription tracking system resulted in a significant reduction in both the cost and number of ER visits and hospital LOS and dramatically decreased opioid consumption.