RT Journal Article
SR Electronic
T1 Prevalence of cerebral venous thrombosis with the use of oral contraceptive pills during the Holy month of Ramadan
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1063
OP 1069
DO 10.15537/smj.2020.10.25397
VO 41
IS 10
A1 Mohammed AlSheef
A1 Mastourah Alotaibi
A1 Abdul Rehman Z. Zaidi
A1 Areej Alshamrani
A1 Aroub Alhamidi
A1 Syed Ziauddin A. Zaidi
A1 Noor Alanazi
A1 Sarah Alhathlool
A1 Ohoud Alarfaj
A1 Mohammed AlHazzaa
A1 Ghaydaa Kullab
A1 Amany Alboghdadly
A1 Amani Abu-Shaheen
YR 2020
UL http://smj.org.sa/content/41/10/1063.abstract
AB Objectives: To identify the epidemiologic profile of cerebral vein thrombosis (CVT) among fasting women using oral contraceptive pills (OCPs) during the holy month of Ramadan.Methods: This retrospective study was conducted on all patients diagnosed with CVT and using OCPs from records at a tertiary care hospital in Riyadh, Saudi Arabia during 2016-2017. The study participants were categorized into 2 groups (an intermittently fasting group during the holy month of Ramadan and a non-fasting group).Results: Out of 108 female patients with CVT, 36.1% were secondary to OCP, of whom 41% participants were fasting. The most affected site was the transverse sinus. Holocephalic headache was more common amongst fasting group (68.8%) compared to non-fasting group (30.4%) (p=0.025). Dehydration (p=0.003) amongst the fasting group and protein S deficiency (p=0.027) in the non-fasting group were identified as the 2 prominent risk factors. Unfractionated heparin was the most common anticoagulant therapies used during the initiation phase for non-fasting (36.4%) and fasting groups (50%).Conclusion: All women who are using OCP should undergo formal written risk assessments for factors of CVT. Our study suggests that the negative effects of OCPs use might outweigh its benefits; thus, it should be prescribed with caution, more so in fasting patients.