RT Journal Article
SR Electronic
T1 Role of fine-needle aspiration cytology in evaluating thyroid nodules
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1098
OP 1103
DO 10.15537/smj.2020.10.25417
VO 41
IS 10
A1 Ahmed S. Bahaj
A1 Haddad H. Alkaff
A1 Bashair N. Melebari
A1 Anwar N. Melebari
A1 Suhail I. Sayed
A1 Syeddah S. Mujtaba
A1 Sherif K. Abdelmonim
A1 Saeed A. Alghamdi
A1 Fares E. Alghamdi
A1 Omar A. Abu Suliman
A1 Mohammad A. Alessa
A1 Firas R. Abi Sheffah
A1 Anas H. Al-Tammas
A1 Rajab A. Al-Zahrani
A1 Osama A. Marglani
A1 John C. Heaphy
A1 Osama A. Bawazir
A1 Ameen Z. Alherabi
YR 2020
UL http://smj.org.sa/content/41/10/1098.abstract
AB Objectives: To evaluate the accuracy and efficacy of fine-needle aspiration cytology (FNAC) in diagnosing thyroid nodules, correlating it with the histopathological findings.Methods: A retrospective evaluation of 314 patients was undertaken at a tertiary referral center of King Abdullah Medical City (KAMC), Makkah, Kingdom of Saudi Arabia, between 2010-2019. Patients who presented with thyroid swellings underwent ultrasonography and FNAC. If indicated, surgery was performed. The FNAC findings were compared to the final histopathological reports.Results: The findings for FNAC from our data set of 314 patients showed a sensitivity value of 79.8%, specificity of 82.1%, accuracy of 74.8%, positive predictive value of 74.8%, and negative predictive value of 85.9%.Conclusion: Our study showed that FNAC has high sensitivity and specificity in the initial evaluation of patients with thyroid nodules. When guided by ultrasonography, the accuracy can be markedly improved. Molecular markers once widely available can improve the diagnostic power of FNAC to be no less than the histopathologic evaluation of thyroid tissue.