@article {Safioleas1748, author = {Michael C. Safioleas and Michael C. Stamatakos and Ahmad I. Diab and Panagiotis M. Safioleas}, title = {The use of oxygen in Fournier{\textquoteright}s gangrene}, volume = {27}, number = {11}, pages = {1748--1750}, year = {2006}, publisher = {Saudi Medical Journal}, abstract = {Fournier{\textquoteright}s gangrene is an aggressive form of necrotizing fasciitis of the perineal, perianal or genital regions, usually caused by a polymicrobial infection that includes virulent organisms. Over the last decades, we have treated 9 patients suffering from Fournier{\textquoteright}s gangrene using systemic chemotherapy with broad-spectrum antibiotics, and with extensive, sometimes serial surgical debridement. Recently in one case, in addition to treatment, we used locally 100\% oxygen in daily doses with promising results in healing wound. Herein, we report this case with a brief review of the literature concerning pathogenesis, risk factors, and treatment approaches.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/27/11/1748}, eprint = {https://smj.org.sa/content/27/11/1748.full.pdf}, journal = {Saudi Medical Journal} }