PT  - JOURNAL ARTICLE
AU  - Safioleas, Michael C.
AU  - Stamatakos, Michael C.
AU  - Diab, Ahmad I.
AU  - Safioleas, Panagiotis M.
TI  - The use of oxygen in Fournier's gangrene
DP  - 2006 Nov 01
TA  - Saudi Medical Journal
PG  - 1748--1750
VI  - 27
IP  - 11
4099  - http://smj.org.sa/content/27/11/1748.short
4100  - http://smj.org.sa/content/27/11/1748.full
SO  - Saudi Med J2006 Nov 01; 27
AB  - Fournier's gangrene is an aggressive form of necrotizing fasciitis of the perineal, perianal or genital regions, usually caused by a polymicrobial infection that includes virulent organisms. Over the last decades, we have treated 9 patients suffering from Fournier's gangrene using systemic chemotherapy with broad-spectrum antibiotics, and with extensive, sometimes serial surgical debridement. Recently in one case, in addition to treatment, we used locally 100% oxygen in daily doses with promising results in healing wound. Herein, we report this case with a brief review of the literature concerning pathogenesis, risk factors, and treatment approaches.