TY - JOUR T1 - The use of oxygen in Fournier's gangrene JF - Saudi Medical Journal JO - Saudi Med J SP - 1748 LP - 1750 VL - 27 IS - 11 AU - Michael C. Safioleas AU - Michael C. Stamatakos AU - Ahmad I. Diab AU - Panagiotis M. Safioleas Y1 - 2006/11/01 UR - http://smj.org.sa/content/27/11/1748.abstract N2 - Fournier's gangrene is an aggressive form of necrotizing fasciitis of the perineal, perianal or genital regions, usually caused by a polymicrobial infection that includes virulent organisms. Over the last decades, we have treated 9 patients suffering from Fournier's gangrene using systemic chemotherapy with broad-spectrum antibiotics, and with extensive, sometimes serial surgical debridement. Recently in one case, in addition to treatment, we used locally 100% oxygen in daily doses with promising results in healing wound. Herein, we report this case with a brief review of the literature concerning pathogenesis, risk factors, and treatment approaches. ER -