RT Journal Article
SR Electronic
T1 The use of oxygen in Fournier's gangrene
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1748
OP 1750
VO 27
IS 11
A1 Safioleas, Michael C.
A1 Stamatakos, Michael C.
A1 Diab, Ahmad I.
A1 Safioleas, Panagiotis M.
YR 2006
UL http://smj.org.sa/content/27/11/1748.abstract
AB Fournier's gangrene is an aggressive form of necrotizing fasciitis of the perineal, perianal or genital regions, usually caused by a polymicrobial infection that includes virulent organisms. Over the last decades, we have treated 9 patients suffering from Fournier's gangrene using systemic chemotherapy with broad-spectrum antibiotics, and with extensive, sometimes serial surgical debridement. Recently in one case, in addition to treatment, we used locally 100% oxygen in daily doses with promising results in healing wound. Herein, we report this case with a brief review of the literature concerning pathogenesis, risk factors, and treatment approaches.