TY - JOUR T1 - Evaluation of the effect of Bupivacaine (Marcaine) in reducing early post tonsillectomy pain JF - Saudi Medical Journal JO - Saudi Med J SP - 1201 LP - 1204 VL - 33 IS - 11 AU - Manal A. Bukhari AU - Abdulmalik S. Al-Saied Y1 - 2012/11/01 UR - http://smj.org.sa/content/33/11/1201.abstract N2 - OBJECTIVE: To evaluate the effectiveness of bupivacaine as topically applied in reducing post tonsillectomy pain within the first 24 hours.METHODS: This prospective, randomized, placebo-controlled, intra-individual, single-blind study was conducted at the Otolaryngology Department, King Abdulaziz University Hospital, King Saud University, Riyadh, Kingdom of Saudi Arabia from October 2009 until March 2010. Thirty-five patients underwent cold knife tonsillectomy. One tonsillar fossa was packed with gauze soaked in plain 0.25% bupivacaine, while the other tonsillar fossa was packed with gauze soaked in normal saline (the control side). Both gauzes were applied for 5 minutes. The patients' pain was evaluated on each side using the visual analog scale at 2, 4, 6, 12, and 24 hours post-operatively.RESULTS: The reduction in pain at 2 and 4 hours was statistically insignificant compared with the control side. However, at 6, 12, and 24 hours post operatively, the reduction of pain was statistically significant.CONCLUSION: Topical application of bupivacaine at a 0.25% concentration appears to a considerable degree of analgesia within the first 24 hours post tonsillectomy. ER -