RT Journal Article SR Electronic T1 COVID-19 in children ranging from asymptomatic to a multi-system inflammatory disease JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 299 OP 305 DO 10.15537/smj.2021.42.3.20200625 VO 42 IS 3 A1 Shahin, Walaa A1 Rabie, Walaa A1 Alyossof, Osama A1 Alasiri, Mohammed A1 Alfaki, Mohamed A1 Mahmoud, Elamin A1 Hijazi, Muwaffak A1 Faraidi, Huda El A1 Alahmari, Hassan YR 2021 UL http://smj.org.sa/content/42/3/299.abstract AB Objectives: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19.Methods: Eighty-eight children (0-14 years) with COVID-19 who were admitted to Prince Sultan Military Medical City (PSMMC), Riyadh, Saudi Arabia from April to June 2020 were recruited.Results: Mean age was 5.74 ± 4.7 years with 41 (49.4%) males and 42 (50.6%) females. The length of hospital stay (LOS) ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein (CRP), serum ferritin, and lactate dehydrogenase (LDH) were noticeably above normal. Degree of severity and length of stay was significantly correlated with lymphopenia (r= -0.36; p=0.001), whereas it was positively correlated with absolute neutrophil count and with high inflammatory markers, such as CRP, LDH, and others.Conclusions: Identifying the clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 will improve understanding of this disease’s presentation and will help put rapid and proper management strategies into place to face this pandemic. A high index of suspicion is needed for cases presenting with multi-system inflammatory disease, which represented 5.7% of the included study population.