RT Journal Article
SR Electronic
T1 Progeria with post-streptococcal glomerulonephritis. A rare case report with differential diagnosis
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 190
OP 194
VO 34
IS 2
A1 Sebastian, Alphy A.
A1 Ahsan, Auswaf K.
YR 2013
UL http://smj.org.sa/content/34/2/190.abstract
AB Hutchinson-Gilford progeria syndrome is a rare autosomal dominant disorder associated with skin fragility. It is characterized by craniofacial disproportion, delayed dentition, micrognathia, and plucked bird appearance. The genetic defect is mainly de nova mutation in the lamin A gene. This report describes a 16-year-old patient with classical features of progeria along with post-streptococcal glomerulonephritis. The symptoms of hepatomegaly were also present in the patient. The differential diagnoses of this lesion are also discussed in detail in this literature.