PT - JOURNAL ARTICLE AU - Huseyin Per AU - Mehmet Canpolat AU - Ugur Sahin AU - Hakan Gumus AU - Bahadir Konuskan AU - Sefer Kumandas TI - Serum and urine boron and selenium levels in children with resistant epilepsy DP - 2012 Sep 01 TA - Saudi Medical Journal PG - 942--947 VI - 33 IP - 9 4099 - http://smj.org.sa/content/33/9/942.short 4100 - http://smj.org.sa/content/33/9/942.full SO - Saudi Med J2012 Sep 01; 33 AB - OBJECTIVE: To determine the role of serum and urine selenium, and boron levels in children with resistant epilepsy.METHODS: Serum and urine boron and selenium levels were studied in 53 cases (32 boys and 21 girls) diagnosed with resistant epilepsy between April 2006 and February 2007 at the Department of Pediatric Neurology, Erciyes University, Kayseri, Turkey. Differences between groups were assessed using Student's t-test. Countable data were defined as percentage. Inter-group difference was assessed by Chi-square test. P-values less than 0.05 were considered significant.RESULTS: When serum and urine boron and selenium levels were evaluated and compare with controls, a statistically significant difference was found in serum selenium, urine selenium, and urine boron levels (p<0.05). No significant difference was found in serum boron levels (p>0.05).CONCLUSION: It was observed that there is a need for selenium supplementation in treatment of patients with resistant epilepsy, while no etiologic role is observed for boron.