PT  - JOURNAL ARTICLE
AU  - Per, Huseyin
AU  - Canpolat, Mehmet
AU  - Sahin, Ugur
AU  - Gumus, Hakan
AU  - Konuskan, Bahadir
AU  - Kumandas, Sefer
TI  - Serum and urine boron and selenium levels in children with resistant epilepsy
DP  - 2012 Sep 01
TA  - Saudi Medical Journal
PG  - 942--947
VI  - 33
IP  - 9
4099  - http://smj.org.sa/content/33/9/942.short
4100  - http://smj.org.sa/content/33/9/942.full
SO  - Saudi Med J2012 Sep 01; 33
AB  - OBJECTIVE: To determine the role of serum and urine selenium, and boron levels in children with resistant epilepsy.METHODS: Serum and urine boron and selenium levels were studied in 53 cases (32 boys and 21 girls) diagnosed with resistant epilepsy between April 2006 and February 2007 at the Department of Pediatric Neurology, Erciyes University, Kayseri, Turkey. Differences between groups were assessed using Student's t-test. Countable data were defined as percentage. Inter-group difference was assessed by Chi-square test. P-values less than 0.05 were considered significant.RESULTS: When serum and urine boron and selenium levels were evaluated and compare with controls, a statistically significant difference was found in serum selenium, urine selenium, and urine boron levels (p<0.05). No significant difference was found in serum boron levels (p>0.05).CONCLUSION: It was observed that there is a need for selenium supplementation in treatment of patients with resistant epilepsy, while no etiologic role is observed for boron.