PT  - JOURNAL ARTICLE
AU  - Wang, Jinguo
AU  - Zhao, Haixiao
AU  - Li, Yanhui
AU  - Wang, Rui
AU  - Wang, Na
TI  - Clonidine versus tramadol for post spinal anesthesia shivering
AID  - 10.15537/smj.2021.42.4.20200342
DP  - 2021 Apr 01
TA  - Saudi Medical Journal
PG  - 363--369
VI  - 42
IP  - 4
4099  - http://smj.org.sa/content/42/4/363.short
4100  - http://smj.org.sa/content/42/4/363.full
SO  - Saudi Med J2021 Apr 01; 42
AB  - Objectives: To compare clonidine with tramadol for shivering control following spinal anesthesia.Methods: The literature was searched updated to August 2020, and only randomized controlled trials comparing clonidine and tramadol for shivering control following spinal anesthesia were eligible for this study.Results: Fourteen studies with 960 patients were identified. Clonidine demonstrated a lower effective rate of shivering control (OR: 0.59; 95% CI: 0.40-0.88; p=0.009; I2=36%), but with decreased occurrence of nausea, vomiting, and dizziness. Clonidine increased the occurrence of bradycardia, hypotension, and sedation compared to tramadol.Conclusion: Tramadol is more effective for shivering control than clonidine, but with increased occurrence of nausea, vomiting, and dizziness.PROSPERO No: CRD42020207979