@article {Albasri449, author = {Abdulkader M. Albasri and Irfan A. Ansari}, title = {Pattern of cancers in adolescent and young adults.}, volume = {42}, number = {4}, pages = {449--453}, year = {2021}, doi = {10.15537/smj.2021.42.4.20210028}, publisher = {Saudi Medical Journal}, abstract = {Objectives: To evaluate the incidence and pattern of cancer in adolescents and young adults (AYAs) age group in Al-Madinah Al-Munawwarah region of Saudi Arabia.Methods: This retrospective histopathology-based study was conducted at a tertiary care center in Al-Madinah Al-Munawwarah, Saudi Arabia and comprised cases of cancers for 15 years between January 2006 and December 2020.Results: During the last 15-year period, 8,769 cases of cancers were diagnosed out of which 475 (5.4\%) cases were registered in AYAs. Of these cases, 232 (48.8\%) were males while 243 (51.2\%) were females, with a male-to-female ratio of 0.9:1. The 3 most common cancer groups in the entire cohort were carcinomas (n=165; 34.7\%), lymphomas (n=135; 28.4\%), and leukemias (n=91; 19.2\%). The most common sites in carcinomas were thyroid (n=60; 12.6\%), breast (n=35; 7.4\%), and gastrointestinal (n=18; 3.8\%). The leading cancers in males were the lymphomas (n=74; 15.6\%), leukemias (n=57; 12\%), bone (n=21; 4.4\%), and central nervous system (n=20; 4.2\%), while in females, the most common cancers were the lymphomas (n=61; 12.8\%), thyroid (n=40; 8.4\%), breast (n=34; 7.2\%), and leukemias (n=34; 7.2\%).Conclusion: Our findings are in concordance with studies in national and international literature and we believe that our study provides a baseline tool for future population-targeted studies.}, issn = {0379-5284}, URL = {https://smj.org.sa/content/42/4/449}, eprint = {https://smj.org.sa/content/42/4/449.full.pdf}, journal = {Saudi Medical Journal} }