PT  - JOURNAL ARTICLE
AU  - Albasri, Abdulkader M.
AU  - Ansari, Irfan A.
TI  - Pattern of cancers in adolescent and young adults.
AID  - 10.15537/smj.2021.42.4.20210028
DP  - 2021 Apr 01
TA  - Saudi Medical Journal
PG  - 449--453
VI  - 42
IP  - 4
4099  - http://smj.org.sa/content/42/4/449.short
4100  - http://smj.org.sa/content/42/4/449.full
SO  - Saudi Med J2021 Apr 01; 42
AB  - Objectives: To evaluate the incidence and pattern of cancer in adolescents and young adults (AYAs) age group in Al-Madinah Al-Munawwarah region of Saudi Arabia.Methods: This retrospective histopathology-based study was conducted at a tertiary care center in Al-Madinah Al-Munawwarah, Saudi Arabia and comprised cases of cancers for 15 years between January 2006 and December 2020.Results: During the last 15-year period, 8,769 cases of cancers were diagnosed out of which 475 (5.4%) cases were registered in AYAs. Of these cases, 232 (48.8%) were males while 243 (51.2%) were females, with a male-to-female ratio of 0.9:1. The 3 most common cancer groups in the entire cohort were carcinomas (n=165; 34.7%), lymphomas (n=135; 28.4%), and leukemias (n=91; 19.2%). The most common sites in carcinomas were thyroid (n=60; 12.6%), breast (n=35; 7.4%), and gastrointestinal (n=18; 3.8%). The leading cancers in males were the lymphomas (n=74; 15.6%), leukemias (n=57; 12%), bone (n=21; 4.4%), and central nervous system (n=20; 4.2%), while in females, the most common cancers were the lymphomas (n=61; 12.8%), thyroid (n=40; 8.4%), breast (n=34; 7.2%), and leukemias (n=34; 7.2%).Conclusion: Our findings are in concordance with studies in national and international literature and we believe that our study provides a baseline tool for future population-targeted studies.