RT Journal Article SR Electronic T1 Prevalence and characteristics of autistic children attending autism centres in 2 major cities in Saudi Arabia JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 419 OP 427 DO 10.15537/smj.2021.42.4.20200630 VO 42 IS 4 A1 Heba J. Sabbagh A1 Basma A. Al-Jabri A1 Malek A. Alsulami A1 Lutfi A. Hashem A1 Ala A. Aljubour A1 Rana A. Alamoudi YR 2021 UL http://smj.org.sa/content/42/4/419.abstract AB Objectives: To assess the prevalence and characteristics of Autism Spectrum Disorder (ASD)-affected children attending autistic centers in 2 major cities in Saudi Arabia.Methods: A cross-sectional study, including ASD centers and schools (37 centers) in Makkah and Jeddah, Saudi Arabia was conducted between January and March 2020. Data were collected from records and parents of children with ASD using a questionnaire on sociodemographic, family history, consanguinity, severity, and maternal risk factors.Results: All centers in Makkah and Jeddah participated, with a total of 1,023 ASD children. The prevalence of ASD was 2.618 per 1,000 children for Jeddah, 3.68 per 1,000 children for Makkah and 2.81 per 1,000 children for both Jeddah and Makkah. There was no statistically significant relationship between the severity of ASD and sociodemographic, family and maternal risk factors. However, there was statistically significant relationship between severe ASD and ASD family history (p=0.029, OR: 3.46 and 95% CI 1.14 to 10.5).Conclusions: The prevalence of ASD in Makkah and Jeddah was lower than the global prevalence of ASD. Individuals with a family history of ASD were more likely to have more severe ASD.