PT - JOURNAL ARTICLE AU - Hani N. Mufti AU - Ahmed A. Rabie AU - Alyaa M. Elhazmi AU - Husam A. Bahaudden AU - Mostafa A. Rajab AU - Ismael S. Al Enezi AU - Ayed Y. Assiri AU - Khalid A. Maghrabi AU - Ali A. Al Bshabshe AU - Abdullah M. Abudayah AU - Adel A. Tash AU - Awad A. Al-Omari AU - Mohamed H. Azzam TI - The Saudi Critical Care Society extracorporeal life support chapter guidance on utilization of veno-venous extracorporeal membrane oxygenation in adults with acute respiratory distress syndrome and special considerations in the era of coronavirus disease 2019 AID - 10.15537/smj.2021.42.6.20200520 DP - 2021 Jun 01 TA - Saudi Medical Journal PG - 589--611 VI - 42 IP - 6 4099 - http://smj.org.sa/content/42/6/589.short 4100 - http://smj.org.sa/content/42/6/589.full SO - Saudi Med J2021 Jun 01; 42 AB - Extracorporeal membrane oxygenation (ECMO) is considered as a supportive treatment that provides circulatory and ventilatory support and can be thought off as a bridge to organ recovery. Since 2009, it has been applied as a rescue treatment for patients with severe adult respiratory distress syndrome (ARDS) mainly due to viral causes. In December 2019, several patients presented with a constellation of symptoms of viral pneumonia in China. A new strain of the corona virus family, called COVID-19, has been discovered to be the cause of this severe mysterious illness that was named severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2). This new virus continued to spread across the globe leading to the World Health Organization announcing it as a pandemic in the early 2020. By the end of March 2021, the number of COVID-19 cases worldwide exceeded 126 million cases. In Saudi Arabia, the first confirmed case of COVID-19 was reported in the 2nd March 2020. By the end of March 2021, the total number of confirmed COVID-19 cases in Saudi Arabia is just above 360,000. In anticipation of the need of ECMO for the treatment of patients with SARS‑CoV‑2 based on the previous Middle East respiratory syndrome coronavirus pandemic experience, the Saudi Extra-Corporeal Life Support (ECLS) chapter that is under the umbrella of the Saudi Critical Care Society (SCCS) convened a working group of ECMO experts. The mission of this group was to formulate a guidance for the use of ECMO as a last resort for patients with severe ARDS, especially with COVID-19 based on available evidence. The ECLS-SCCS chapter wanted to generate a document that can be used to simple guide, with a focus on safety, to provide ECMO service for patients with severe ARDS with a special focus on SARS‑CoV‑2.