PT  - JOURNAL ARTICLE
AU  - Mirkhalig Javadov
AU  - Emrah Karatay
AU  - Mustafa U. Ugurlu
TI  - Clinical and functional results of radiofrequency ablation and microwave ablation in patients with benign thyroid nodules
AID  - 10.15537/smj.2021.42.8.20210307
DP  - 2021 Aug 01
TA  - Saudi Medical Journal
PG  - 838--846
VI  - 42
IP  - 8
4099  - http://smj.org.sa/content/42/8/838.short
4100  - http://smj.org.sa/content/42/8/838.full
SO  - Saudi Med J2021 Aug 01; 42
AB  - Objectives: To determine how well ultrasound-guidance percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) performed for benign symptomatic thyroid nodules in terms of clinical and functional outcomes.Methods: Patients who had a thyroid nodule-linked symptoms acting as dysphagia, cosmetic issues, pain, a foreign body sense, hyperthyroidism secondary to autonomous nodules, or concern of malignancy were involved in the study. The primary was the comparison in symptom scores obtained at 1, 3, and 6 months after RFA and MWA. The volume alterations in nodules and alterations in thyroid gland functions were secondary objectives.Results: This prospective study carried out from November 2014 and January 2017 at the General Surgery Department, Marmara University, Faculty of Medicine, Istanbul, Turkey included a total of 100 nodules (50% MWA, 50% RFA). There were statistically significance in pain scores, dysphagia scores, and foreign body sensation scores at 1, 3, and 6 months after therapy in both ablation groups (p=0.0006, p=00004, p=0.0005). At the same time, there were statistically significant reductions in size and volume of the nodules for RFA and MWA (p=0.0004, p=0.0003). There was no significant difference between the RFA and MWA groups’ cosmetic scoring and volume changes (p=0.68, p=0.43).Conclusions: Alternative therapies for benign symptomatic thyroid nodules include RFA and MWA. The findings of this research revealed that both approaches are safe and effective.