PT - JOURNAL ARTICLE AU - Abeer M. Albaadani AU - Eid A. Alsufyani AU - Mohamed I. Mursi AU - Mohamed H. Haris AU - Kiran K. Kalam AU - Nisreen M. Alsherbeeni AU - Ahmed M. Al-Rumaihi AU - Souad M. Alateah AU - Medina A. Ahmed AU - Moayad M. Alqurashi TI - SARS-CoV-2 seroprevalence among healthcare workers from a tertiary care center in Riyadh, Saudi Arabia AID - 10.15537/smj.2021.42.11.20210391 DP - 2021 Nov 01 TA - Saudi Medical Journal PG - 1243--1246 VI - 42 IP - 11 4099 - http://smj.org.sa/content/42/11/1243.short 4100 - http://smj.org.sa/content/42/11/1243.full SO - Saudi Med J2021 Nov 01; 42 AB - Objectives: To calculate the seroprevalence of asymptomatic healthcare workers (HCWs) in our institution.Methods: We conducted a cross-sectional study among asymptomatic HCWs in a large hospital during the peak of the pandemic (from July to August 2020 and followed them up until February 2021) in Riyadh, Saudi Arabia. We collected the data in a Microsoft Word document after collecting a single serum sample for detection of antibodies from each participant then we compared the results statically in Microsoft Excel tables.Results: We enrolled 188 participants and measured their IgG antibodies from venous blood samples using CLIA. Six (3.2%) had positive antibodies despite being asymptomatic. Most of these were from non-COVID-19 working areas (4 out of 6), but all had an exposure with a positive COVID-19 patient at some point in the preceding 2 months.Conclusions: Our results are consistent with similar local studies showing low seroprevalence among HCWs while most positive cases are from non-COVID-19 areas. Despite this low seroprevalence, HCWs are still considered a high-risk group; hence, there is a need to encourage strict implementation and adherence to infection control measures and vaccination among HCWs, especially when these measures are relaxed on the national level.