RT Journal Article SR Electronic T1 SARS-CoV-2 seroprevalence among healthcare workers from a tertiary care center in Riyadh, Saudi Arabia JF Saudi Medical Journal JO Saudi Med J FD Prince Sultan Military Medical City SP 1243 OP 1246 DO 10.15537/smj.2021.42.11.20210391 VO 42 IS 11 A1 Abeer M. Albaadani A1 Eid A. Alsufyani A1 Mohamed I. Mursi A1 Mohamed H. Haris A1 Kiran K. Kalam A1 Nisreen M. Alsherbeeni A1 Ahmed M. Al-Rumaihi A1 Souad M. Alateah A1 Medina A. Ahmed A1 Moayad M. Alqurashi YR 2021 UL http://smj.org.sa/content/42/11/1243.abstract AB Objectives: To calculate the seroprevalence of asymptomatic healthcare workers (HCWs) in our institution.Methods: We conducted a cross-sectional study among asymptomatic HCWs in a large hospital during the peak of the pandemic (from July to August 2020 and followed them up until February 2021) in Riyadh, Saudi Arabia. We collected the data in a Microsoft Word document after collecting a single serum sample for detection of antibodies from each participant then we compared the results statically in Microsoft Excel tables.Results: We enrolled 188 participants and measured their IgG antibodies from venous blood samples using CLIA. Six (3.2%) had positive antibodies despite being asymptomatic. Most of these were from non-COVID-19 working areas (4 out of 6), but all had an exposure with a positive COVID-19 patient at some point in the preceding 2 months.Conclusions: Our results are consistent with similar local studies showing low seroprevalence among HCWs while most positive cases are from non-COVID-19 areas. Despite this low seroprevalence, HCWs are still considered a high-risk group; hence, there is a need to encourage strict implementation and adherence to infection control measures and vaccination among HCWs, especially when these measures are relaxed on the national level.