PT  - JOURNAL ARTICLE
AU  - Alkhlewi, Moayed N.
AU  - Al-Dorzi, Hasan M.
AU  - Alenezi, Farhan Z.
AU  - Farhat, Abdulrahman M.
AU  - Tamim, Hani
AU  - Sadat, Musharaf
AU  - Humaid, Felwa Bin
AU  - Arabi, Yaseen M.
TI  - Outcomes of cirrhotic patients admitted to the intensive care unit after a successful cardiac arrest resuscitation
AID  - 10.15537/smj.2021.42.12.20210478
DP  - 2021 Dec 01
TA  - Saudi Medical Journal
PG  - 1320--1324
VI  - 42
IP  - 12
4099  - http://smj.org.sa/content/42/12/1320.short
4100  - http://smj.org.sa/content/42/12/1320.full
SO  - Saudi Med J2021 Dec 01; 42
AB  - Objectives: To evaluate the outcomes of cirrhotic patients admitted to the intensive care unit (ICU) following cardiac arrest.Methods: This was a single centre retrospective study of all the cirrhotic patients, admitted to the ICU at King Abdulaziz Medical City, Riyadh, Saudi Arabia, after a successful cardiac arrest resuscitation, from 1999 to 2017. The characteristics of the hospital survivors and non-survivors were compared.Results: A total of 76 patients were admitted to the ICU during the study period, with a median age of 64 years. In addition to cirrhosis, the patients had other chronic comorbidities, including chronic renal disease (32.9%) and diabetes (47%). Of this group, 67 (88.2%) died in the hospital, and 54 (71%) died while in ICU. Compared to the group who survived, all non-survivors required mechanical ventilation and had a higher median APACHE II score of 38 (p=0.006), a lower median Glasgow coma score (GCS) of 3 (p=0.0003), and a higher median lactic acid of 6.4 mmol/L (p=0.032). On multivariable logistic regression analysis, the important predictors of hospital mortality were APACHE II score (p=0.006), bilirubin level (p=0.008) and GCS (p=0.005).Conclusion: Cirrhotic patients admitted to the ICU following cardiac arrest have high mortality. Patients with higher APACHE II scores, higher bilirubin and lower GCS have higher risk of in-hospital mortality.