RT Journal Article
SR Electronic
T1 Lymph node yield as a prognostic factor in clinically node negative oral cavity squamous cell carcinoma
JF Saudi Medical Journal
JO Saudi Med J
FD Prince Sultan Military Medical City
SP 1357
OP 1361
DO 10.15537/smj.2021.42.12.20210572
VO 42
IS 12
A1 Ahmad A. AlTuwaijri
A1 Mohammed A. Alessa
A1 Alanoud A. Abuhaimed
A1 Reenad H. Bedaiwi
A1 Mohammad A. Almayouf
A1 Majed M. Albarrak
A1 Saleh F. Aldhahri
A1 Khalid H. Al-Qahtani
YR 2021
UL http://smj.org.sa/content/42/12/1357.abstract
AB Objectives: To determine the prognostic significance of nodal yield in patients with clinically node-negative (cN0) oral cavity squamous cell carcinoma (OCSCC).Methods: This retrospective observational study included 40 patients with cN0 OCSCC who underwent treatment with at least 6 months of follow-up data from November 2012 to April 2020. We recorded the variables, including patient demographics, cancer site, tumor-node-metastasis (TNM) staging, type of treatment, lymph node yield (LNY), histopathologic diagnosis, and recurrence. The recorded data were analyzed with descriptive and interferential statistics using specific tests.Results: Our study cohort comprised of 27 males and 13 females with a mean age of 60.08+13.153 years. Tongue (55%) was the commonly affected site. Seventeen (42.5%) patients belonged to TNM stage II. The mean LNY in our study was 38.65±25.41 (range 7-98). Following surgery, 19 (47.5%) patients further received adjuvant therapies. Recurrence was reported only in 4 (10%) patients. There was no significant difference between LNY and recurrence rate (p=0.892). Factors including, age (p=0.121), gender (p=0.209), site (p=0.519), size of tumor (p=0.416) did not influence the LNY.Conclusion: There is no correlation between LNY and recurrence in cN0 OCSCC patients in our study. Meticulous neck dissection and thorough pathologic reporting prevents TNM under staging and improves the overall survival and prognosis.